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Published on: February 17, 2023
Insulin resistance in children
Francesca Mainieri1, Veronica Maria Tagi, Francesco Chiarelli
1Department of Paediatrics, University of Chieti, Chieti, Italy.
Insights
Insulin resistance (IR) in children is a growing global health issue. This review covers IR
Area of Science:
- Pediatric Endocrinology
- Metabolic Health
- Public Health
Background:
- Insulin resistance (IR) impairs the body's ability to regulate blood glucose.
- IR is increasingly recognized as a significant global health concern.
- Childhood IR is linked to various chronic metabolic diseases.
Purpose of the Study:
- To provide a comprehensive overview of current knowledge on pediatric IR.
- To focus on the pathophysiology, measurement, risk factors, effects, screening, and treatment of IR in children.
Main Methods:
- This is a review article.
- It synthesizes existing research on pediatric insulin resistance.
Main Results:
- IR in children is a complex condition with significant health implications.
- Accurate measurement and identification of risk predictors are crucial for managing IR.
- Early detection and intervention are key to reducing the incidence of IR and associated metabolic diseases.
Conclusions:
- Addressing pediatric IR is a critical public health challenge.
- Further research is needed to refine diagnostic methods and therapeutic strategies.
- A multi-faceted approach is required for effective screening and treatment of IR in children.
Purpose Of Review:
Insulin resistance (IR) is a clinical condition due to the decline in the efficiency of insulin promoting glucose uptake and utilization. The aim of this review is to provide an overview of the current knowledge on IR in children, focusing on its physiopathology, the most appropriate methods of measurement of IR, the assessment of risk factors, the effects of IR in children, and finally giving indications on screening and treatment.
Recent Findings:
IR has evolved more and more to be a global public health problem associated with several chronic metabolic diseases.
Summary:
Detecting a correct measurement method and specific risk predictors, in order to reduce the incidence of IR, represents a challenging goal.
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