Related Experiment Video
Updated: Sep 5, 2025

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
Published on: June 6, 2020
Contextual Conversational Agent to Address Vaccine Hesitancy: Protocol for a Design-Based Research Study
Youness Zidoun1, Sreelekshmi Kaladhara1, Leigh Powell1
1Institute for Excellence in Health Professions Education, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Design-based research (DBR) is used to create conversational agents (CAs) that combat vaccine hesitancy. This iterative process aims to enhance CA accuracy and performance in delivering crucial health information.
Area of Science:
- Health communication
- Human-computer interaction
- Artificial intelligence in healthcare
Background:
- Misinformation regarding COVID-19 and vaccines is widespread.
- Health organizations utilize conversational agents (CAs) to combat misinformation.
- Effective CA design is crucial for successful health communication strategies.
Purpose of the Study:
- To describe the application of design-based research (DBR) for contextual CA design.
- To address vaccine hesitancy through tailored CA development.
- To examine DBR's impact on CA accuracy and performance.
Main Methods:
- Utilized a design-based research (DBR) methodology with iterative cycles of analysis, design, and evaluation.
- Employed the System Usability Scale for user perception assessment.
- Adopted the PARADISE (PARAdigm for Dialogue System Evaluation) method for performance calculation of the text-based CA.
Main Results:
- Completed the design and evaluation phases of the first DBR cycle.
- Currently refining the natural-language understanding model for pilot intervention.
- Planning three DBR cycles with expected results from the first cycle by end of 2022.
Conclusions:
- Conversational agents (CAs) offer an innovative channel for health information dissemination.
- Careful design is essential for CAs aiming for behavioral change or health education.
- DBR provides a framework for understanding and optimizing CA development for health communication.
Related Concept Videos
Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Vaccinations
Ethics in Research
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Desensitization and Tachyphylaxis
Immune Response Against Viral Pathogens
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...

