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Assessment of cardiac function in children by strain imaging and its correlation with conventional echocardiographic
Suman Chatterjee1, Somnath Mukherjee2, Neha Rani3
1Department of Cardiology, BM Birla Heart Research Centre, Kolkata, West Bengal, India.
Insights
This study established normal age-dependent longitudinal strain values in children. Conventional echocardiographic parameters did not correlate with these global longitudinal strain values in pediatric populations.
Area of Science:
- Pediatric Cardiology
- Echocardiography
- Cardiac Function Assessment
Background:
- Establishing normal reference values for cardiac function in children is crucial for accurate diagnosis.
- Longitudinal strain analysis provides sensitive insights into myocardial deformation.
- Age-dependent variations in cardiac parameters require specific pediatric reference ranges.
Purpose of the Study:
- To determine normal age-dependent reference values for left ventricular (LV) and right ventricular (RV) global longitudinal strain (GLS) in healthy children.
- To investigate the correlation between GLS and conventional echocardiographic parameters in pediatric subjects.
Main Methods:
- 100 healthy children aged 2-15 years were categorized into three age groups (2-5, 5-10, 10-15 years).
- GE Vivid 7 ultrasound platform with 4 or 7 MHz probes was used for data acquisition.
- LV and RV global longitudinal strains and conventional echocardiographic parameters were measured.
Main Results:
- Mean LVGLS values ranged from -19.89 to -21.48 across age groups; mean RVGLS values ranged from -16.62 to -28.19.
- No significant age-related increase in LVGLS from base to apex was observed.
- No significant correlation was found between GLS (LV or RV) and conventional echocardiographic parameters.
Conclusions:
- Normal age-dependent reference values for LVGLS and RVGLS in children were established.
- Conventional echocardiographic parameters do not correlate with GLS in healthy children.
- These findings aid in the interpretation of cardiac function in pediatric populations using strain imaging.
Background:
The objectives of this study were to find out of normal reference value for age-dependent longitudinal strain values in children and find its correlation with conventional echocardiographic parameters.
Methods:
In total, 100 healthy normal children aged between 2 and 15 years were enrolled and divided into three age groups, namely, 2-5 years, 5-10 years, and 10-15 years. Using the GE Vivid 7 ultrasound platform with 4 or 7 MHz probes, both LV and RV global longitudinal strains and conventional echocardiographic parameters were acquired.
Results:
In normal healthy children, left ventricular GLS values were -20.10 to -19.68 (mean: -19.89), -21.93 to -21.02 (mean: -21.48), and -20.87 to -20.41 (mean: -20.64)) in children aged 2-5 years, 5-10 years, and 10-15 years and right ventricular GLS values were -16.80 to -16.44 (mean: -16.62), -27.85 to -27.27 (mean: -27.56), -28.44 to -27.93 (mean: -28.19) in the above three groups, respectively. No significant increase was noted in the left ventricular strain value from basal to the apical segment from age group 2 years to 15 years and no gender differences were seen. None of the conventional echocardiographic parameters commonly used to assess the left or right ventricular systolic function had a significant correlation with LVGLS and RVGLS.
Conclusions:
The mean LVGLS values were -19.89, -21.48, and -20.64 and RVGLS were -16.62, -27.56, and -28.19 in healthy normal children aged 2-5 years, 5-10 years, and 10-15 years, respectively, and conventional echocardiographic parameters did not have any significant correlation with these values.
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