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Updated: Sep 5, 2025

Controlled Photoredox Ring-Opening Polymerization of O-Carboxyanhydrides Mediated by Ni/Zn Complexes
Published on: November 21, 2017
Three-component carboacylation of alkenes via cooperative nickelaphotoredox catalysis
Dingyi Wang1, Lutz Ackermann1,2
1Institut für Organische und Biomolekulare Chemie and Wöhler Research Institute for Sustainable Chemistry, Georg-August-Universität Göttingen Tammannstraße 2 37077 Göttingen Germany Lutz.Ackermann@chemie.uni-goettingen.de.
Abstract:
Various commercially available acyl chlorides, aldehydes, and alkanes were exploited for versatile three-component 1,2-carboacylations of alkenes to forge two vicinal C-C bonds through the cooperative action of nickel and sodium decatungstate catalysis. A wealth of ketones with high levels of structural complexity was rapidly obtained via direct functionalization of C(sp2)/C(sp3)-H bonds in a modular manner. Furthermore, a regioselective late-stage modification of natural products showcased the practical utility of the strategy, generally featuring high resource economy and ample substrate scope.
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