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Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease
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Updates in therapeutic drug monitoring in inflammatory bowel disease

Nilesh Lodhia1, Shanti Rao2

  • 1Department of Gastroenterology and Hepatology, Atrium Health, Charlotte, NC 28203, United States. nilesh.lodhia@atriumhealth.org.

World Journal of Gastroenterology
|July 8, 2022
PubMed

Biologics and immunomodulators (IMM) are generally considered the most effective therapies for the treatment of ulcerative colitis and Crohn's disease. However, despite the efficacy of these therapies, many patients either have a primary lack of response or a secondary loss of response to these medications. Therapeutic drug monitoring (TDM) is a systematic approach to managing such patients. In this review, we summarize the latest data on TDM, including reactive and proactive TDM, in patients with inflammatory bowel disease on biologics and/or IMM.

Keywords:
Crohn’s diseaseInflammatory bowel diseaseTherapeutic drug monitoringUlcerative colitis

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