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Related Experiment Video

Updated: Sep 5, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

Hashimoto's encephalopathy with psychiatric presentation.

Apala Singh¹, Linkan Verma²

¹Department of Psychiatry, University College of Medical Sciences, Guru Teg Bahadur Hospital, New Delhi, India.

Industrial Psychiatry Journal

|July 8, 2022

Summary

Hashimoto's encephalopathy, a rare neurological disorder, can manifest with psychiatric symptoms and dementia. Early diagnosis and steroid treatment lead to significant recovery, improving patient prognosis.

Keywords:

Hashimoto's encephalopathy neuropsychiatric presentation steroid-responsive

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Area of Science:

Neurology
Immunology
Psychiatry

Background:

Hashimoto's encephalopathy is a rare autoimmune neurological condition.
It presents with diverse neuropsychiatric symptoms, excluding CNS infection or tumors.

Observation:

A 55-year-old male exhibited progressive dementia and psychiatric disturbances.
The patient's presentation mimicked other neurological and psychiatric disorders.

Findings:

Intravenous steroids and low-dose oral risperidone were administered.
Prompt diagnosis and management led to clinical improvement.

Implications:

This case underscores the importance of considering Hashimoto's encephalopathy in patients with unexplained encephalopathy.
Timely diagnosis and treatment with steroids can result in excellent remission rates and prognosis.