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Treatment of preschool children with obsessive compulsive disorder

Sevim Berrin Inci Izmir1, Eyüp Sabri Ercan2

  • 152967Isik University, Child and Adolescent Clinical Psychology, Istanbul, Turkey.

Clinical Child Psychology and Psychiatry
|July 8, 2022
PubMed

Insights

Aripiprazole combined with Cognitive-Behavioral Family Therapy (CBFT) effectively treats Obsessive-Compulsive Disorder (OCD) in preschoolers. Early intervention is crucial due to frequent comorbidities complicating treatment.

Area of Science:

  • Child and Adolescent Psychiatry
  • Pediatric Mental Health

Background:

  • Obsessive-Compulsive Disorder (OCD) in preschool children presents unique clinical features.
  • Comorbid psychiatric conditions are frequently observed in young children with OCD, potentially complicating treatment outcomes.

Purpose of the Study:

  • To investigate the clinical characteristics of early-onset OCD in preschoolers.
  • To evaluate the efficacy of aripiprazole combined with Cognitive-Behavioral Family Therapy (CBFT) for treating OCD in this age group.

Main Methods:

  • Diagnosis of OCD in 12 preschoolers (36-72 months) based on DSM-5 criteria.
  • Utilized Kiddie Schedule for Affective Disorders and Schizophrenia and Childhood Yale-Brown Obsessive Compulsive Scale (CY-BOCS) for assessments.
  • Treatment involved aripiprazole and standardized CBFT over 24 weeks.

Main Results:

  • Significant reduction in mean total CY-BOCS scores from 33.67 at baseline to 13.83 at 12 weeks and 5.58 at 24 weeks.
  • 66.7% of participants exhibited at least one psychiatric comorbidity.
  • Aripiprazole with CBFT demonstrated a positive effect on OCD symptom severity.

Conclusions:

  • Aripiprazole combined with CBFT is an effective treatment for preschool-aged children with OCD.
  • The high prevalence of comorbidities in preschoolers with OCD necessitates increased awareness and early diagnostic efforts.
  • Early identification and treatment of OCD and its comorbidities in preschoolers are essential for improved outcomes.

Keywords:
Preschoolersaripiprazolechildrencognitive behavioral therapyobsessive compulsive disorder

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