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Published on: June 23, 2022
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Equine Herpesvirus-1 Myeloencephalopathy.
Nicola Pusterla1, Gisela Soboll Hussey2, Lutz S Goehring3
1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA.
The Veterinary Clinics of North America. Equine Practice
|July 10, 2022
Summary
Equine herpesvirus myeloencephalopathy (EHM) is rare but causes significant losses. Early diagnosis via molecular detection and prompt intervention are crucial for managing EHM outbreaks and preventing spread in horse populations.
Area of Science:
- Veterinary Neurology
- Equine Infectious Diseases
- Virology
Background:
- Equine herpesvirus myeloencephalopathy (EHM) is an uncommon but severe neurological condition caused by equine herpesvirus-1 (EHV-1).
- EHM outbreaks can lead to substantial economic losses in the equine industry due to high morbidity and mortality.
- Affected horses pose a significant risk of transmission to susceptible populations.
Purpose of the Study:
- To highlight the importance of early diagnosis and intervention strategies for equine herpesvirus myeloencephalopathy (EHM).
- To emphasize the diagnostic methods and management approaches for EHM.
- To underscore the risks associated with EHM and the need for rapid response.
Main Methods:
- Diagnosis of EHM primarily relies on the molecular detection of EHV-1 in clinical samples such as nasal secretions and blood.
- Clinical signs and epidemiological data are used to support antemortem diagnosis.
- Treatment focuses on supportive care, anti-inflammatory measures, and prevention of complications.
Main Results:
- Molecular detection of EHV-1 in nasal secretions and blood is the cornerstone of antemortem EHM diagnosis.
- Supportive nursing, nutritional care, and anti-inflammatory treatments are key management strategies.
- Prompt isolation and biosecurity measures are essential to control EHM spread.
Conclusions:
- Early and accurate diagnosis of EHM is critical for effective management and control.
- Timely intervention, including biosecurity protocols, is necessary to mitigate the impact of EHM outbreaks.
- Understanding the risks posed by neurologically affected horses is vital for preventing wider dissemination of EHV-1.
