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Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
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Inflammatory Bowel Disease V: Surgical Management01:21

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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Histology of the Large Intestine01:26

Histology of the Large Intestine

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The large intestine, a vital component of the gastrointestinal tract, is structured with four main layers: the mucosa, submucosa, muscularis, and serosa. Each layer performs a distinct role in facilitating the smooth functioning of the large intestine.
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Related Experiment Video

Updated: Sep 5, 2025

Murine Ileocolic Bowel Resection with Primary Anastomosis
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Colonic Intramural Hematoma.

Kimitoshi Kubo1, Noriko Kimura2, Noriaki Hanyu3

  • 1Departments of Gastroenterology, National Hospital Organization Hakodate National Hospital, Hakodate, Japan.

Case Reports in Gastroenterology
|July 11, 2022
PubMed
Summary

This case report details a rare colonic intramural hematoma in an elderly patient treated with anticoagulation. Combined colonoscopy (CS) and computed tomography (CT) effectively diagnosed this submucosal lesion.

Keywords:
AnticoagulationArgatrobanColonoscopyIntramural hematoma

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Area of Science:

  • Gastroenterology
  • Radiology
  • Pathology

Background:

  • Colonic intramural hematoma is a rare condition with poorly documented endoscopic and radiological features.
  • Anticoagulant therapy can predispose patients to gastrointestinal bleeding complications.

Observation:

  • An 82-year-old female presented with hematochezia and anemia after receiving a week of argatroban for acute cerebral infarction.
  • Colonoscopy revealed a large submucosal hematoma in the descending colon with associated mucosal necrosis.
  • Computed tomography confirmed a hyperdense mass in the descending colon.

Findings:

  • The lesion was pathologically confirmed as a subserosal hematoma with full-thickness hemorrhage.
  • Diagnosis was effectively established through the combined use of colonoscopy and computed tomography.
  • Laparoscopic colectomy was performed for the intramural hematoma.

Implications:

  • This case expands the understanding of colonic intramural hematoma presentation and diagnosis.
  • Highlights the utility of combined endoscopic and radiological imaging in diagnosing rare colonic pathologies.
  • Emphasizes the importance of considering intramural hematoma in patients with gastrointestinal bleeding on anticoagulation.