Related Experiment Video
Updated: Sep 5, 2025

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Purely endoscopic appendectomy.
Sergey V Kantsevoy1, Gordon Robbins1, Amit Raina1
1Institute for Digestive Health and Liver Diseases, Mercy Medical Center, Baltimore, Maryland.
This video demonstrates a novel endoscopic technique for resecting a submucosal nodule in the cecum. The procedure utilizes a double-balloon endoluminal interventional platform for safe and effective appendix removal and defect closure.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Minimally Invasive Procedures
Background:
- Submucosal nodules in the cecum can pose diagnostic and therapeutic challenges.
- Traditional surgical approaches may involve significant invasiveness.
Purpose of the Study:
- To showcase a novel endoscopic submucosal dissection technique for cecal submucosal nodules.
- To demonstrate the feasibility of using a double-balloon endoluminal interventional platform (DBEIP) for lesion resection and defect closure.
Main Methods:
- Submucosal injection followed by a circumferential mucosal incision around the lesion.
- Deployment of DBEIP, attachment of mucosal edges to a suture-loop, and traction for lesion retrieval into the cecum.
- Endoscopic submucosal dissection using DualKnife and HookKnife, followed by closure of the full-thickness cecal wall defect with endoscopic suturing.
Main Results:
- Successful endoscopic resection of a submucosal nodule in the cecum.
- Complete closure of the full-thickness cecal wall defect using the Overstitch endoscopic suturing device.
- The entire procedure was performed and visualized endoscopically.
Conclusions:
- This endoscopic technique offers a minimally invasive option for cecal submucosal nodule resection.
- The DBEIP and endoscopic suturing device facilitate safe and effective lesion removal and defect repair.
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