Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effects of postoperative inflammation on visual and refractive recovery after cataract surgery: role of subconjunctival dexamethasone.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026

Same author

Polarimetric entropy mapping of retinal pigment epithelium in full-thickness macular hole by polarization-sensitive OCT.

BMC ophthalmology·2026

Same author

Double-encircling continuous suture technique for complete cyclodialysis: a consecutive case series.

Japanese journal of ophthalmology·2026

Same author

VR-based automated suturing skill assessment in pediatric robotic surgery.

International journal of computer assisted radiology and surgery·2026

Same author

Concurrent vitrectomy with phacoemulsification for subclinical diabetic macular edema: a long-term comparative study.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026

Same author

High-speed liquid switching and on-chip force sensing reveal the transient mechanical response of MscL in <i>Synechocystis</i> sp. PCC 6803.

Lab on a chip·2026

Search research articles

Related Experiment Video

Updated: Sep 5, 2025

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Bionic eye system mimicking microfluidic structure and intraocular pressure for glaucoma surgery training.

Toshiro Yamanaka¹, Tomonori Niino², Seiji Omata³

¹Department of Mechanical Engineering, School of Engineering, The University of Tokyo, Bunkyo, Tokyo, Japan.

|July 11, 2022

Summary

This study introduces a novel surgery simulator for Minimally Invasive Glaucoma Surgery (MIGS) to train ophthalmologists and develop new surgical tools. The simulator accurately models intraocular pressure (IOP) changes during MIGS procedures.

More Related Videos

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Published on: April 24, 2020

Author Spotlight: Advancing Eye Physiology Research via a Multi-Channel Flow Culture for Optimal Tissue Maintenance and Real-Time Assessment

Author Spotlight: Advancing Eye Physiology Research via a Multi-Channel Flow Culture for Optimal Tissue Maintenance and Real-Time Assessment

Published on: July 14, 2023

Related Experiment Videos

Last Updated: Sep 5, 2025

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Published on: April 24, 2020

Author Spotlight: Advancing Eye Physiology Research via a Multi-Channel Flow Culture for Optimal Tissue Maintenance and Real-Time Assessment

Author Spotlight: Advancing Eye Physiology Research via a Multi-Channel Flow Culture for Optimal Tissue Maintenance and Real-Time Assessment

Published on: July 14, 2023

Area of Science:

Ophthalmology
Medical Simulation
Biomedical Engineering

Background:

Glaucoma is a leading cause of vision loss, characterized by optic nerve damage.
Effective treatment for glaucoma involves reducing intraocular pressure (IOP).
Minimally Invasive Glaucoma Surgery (MIGS) offers a less invasive approach to IOP reduction.

Purpose of the Study:

To develop and validate a novel surgery simulator for Minimally Invasive Glaucoma Surgery (MIGS).
To provide a training platform for ophthalmologists performing MIGS procedures.
To facilitate the evaluation and development of new MIGS instruments and robotic systems.

Main Methods:

Designed and manufactured a prototype simulator featuring an anterior eye model with a Schlemm's canal (SC) analog and trabecular meshwork (TM) analog.
Integrated a fluidic circulatory system with a pressure sensor to monitor IOP.
Simulated a MIGS procedure involving TM cleavage and measured IOP changes.

Main Results:

The simulator successfully modeled IOP reduction after TM cleavage.
Experimental results demonstrated the simulator's ability to reflect IOP changes.
The prototype's performance aligned with defined target requirements.

Conclusions:

The developed MIGS simulator is a viable tool for surgical training and procedural practice.
The simulator can be utilized for evaluating new MIGS instruments and ophthalmic surgery robots.
This technology holds promise for advancing glaucoma treatment and surgical innovation.