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Updated: Sep 5, 2025

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
Published on: April 2, 2012
Unusual complication of Herpes simplex encephalitis: complete Klüver-Bucy syndrome
Melissa Hernandez-Vega1, Sandra Badial-Ochoa1, Francisco Javier Rivas-Ruvalcaba1
1Neurology Service, Internal Medicine Department, Hospital Central Dr Ignacio Morones Prieto, San Luis Potosi, Mexico.
Abstract:
Klüver-Bucy syndrome is a rare neurobehavioral disorder caused by a bilateral temporal lobe lesion affecting the hippocampus and amygdala; clinically characterised by hyperorality, hypermetamorphosis, placidity, altered sexual behaviour, eating, disorders and visual impairment, agnosia and amnesia. However, the complete syndrome is rarely seen, and diagnosis does not require all the symptoms to be manifested simultaneously.We describe a patient who developed a complete Klüver-Bucy syndrome secondary to bilateral temporal involvement due to herpetic encephalitis.

