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Induction of Ocular Surface Inflammation and Collection of Involved Tissues
Published on: August 4, 2022
Ocular Inflammatory Reactions following an Inactivated SARS-CoV-2 Vaccine: A Four Case Series
Junhong Ren1, Tingting Zhang1, Xiaoyue Li1
1Department of Ophthalmology, Shanghai Tenth People's Hospital affiliated with Tongji University, Shanghai, China.
Purpose:
To report a four-case series of ocular adverse events post an inactivated COVID-19 vaccination in China.
Methods:
The four patients exhibited ocular inflammatory reactions on the same day after receiving an inactivated SARS-CoV-2 vaccine.
Results:
All patients underwent detailed ophthalmic examinations, with the medical diagnosis of Vogt-Koyanagi-Harada, Ponser-Schlossman, secondary post-inflammatory glaucoma, and iridocyclitis, respectively. No patients had any other underlying medical conditions causing the ocular complications. The ocular inflammatory reactions of these four patients were resolved with the administration of oral or topical corticosteroids.
Conclusion:
Our cases remind the ophthalmologist that adverse ocular events may happen after the administration of SARS-CoV-2 vaccine. Since the ocular complications could be resolved with the corticosteroid treatment, the events were considered to be inflammatory reactions caused by the SARS-CoV-2 vaccine.
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