Related Experiment Video
Updated: Sep 5, 2025

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
Published on: June 24, 2015
On Spiking Neural Membrane Systems with Neuron and Synapse Creation
Marco Gatti1, Alberto Leporati1, Claudio Zandron1
1Dipartimento di Informatica, Sistemistica e Comunicazione, Università degli Studi di Milano-Bicocca, Viale Sarca 336/14, Milano 20126, Italy.
Abstract:
Spiking neural membrane systems are models of computation inspired by the natural functioning of the brain using the concepts of neurons and synapses, and represent a way of building computational systems of a biological inspiration. A variant of such a model, allowing to create new neurons and synapses during the computation, has been considered in the literature to attack computationally hard problems, like problems in the class NP. In this work, we investigate the computational properties of this variant, by proposing three solutions to computationally hard problems, by models with different features, and comparing them with those present in the literature. In particular, we first propose a nondeterministic solution for the NP-complete problem 3-SAT, by a model using dynamic organization of synapses. Then, we propose a deterministic solution for the same problem, by a model using neuron division and dissolution rules. Finally, we show that dissolution rules are not strictly necessary (by accepting a certain amount of slowdown in computing time), and that also problems beyond the class NP can be solved by systems with neuron division alone.
Related Concept Videos
The Synapse
Synaptic Signaling
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...
Integration of Synaptic Events
Neuronal Communication
Neuron Structure
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
Neural Circuits
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...

