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[Cutaneous diphtheria from Africa].

K Fleischer, B Köhler, M Pöllath

    Deutsche Medizinische Wochenschrift (1946)
    |May 29, 1987
    PubMed
    Summary

    Despite diphtheria immunization, a mother contracted cutaneous diphtheria and transmitted Corynebacterium diphtheria to her asymptomatic son. This highlights potential gaps in vaccine efficacy or exposure risks in endemic areas.

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    Area of Science:

    • Infectious Diseases
    • Microbiology
    • Public Health

    Background:

    • Diphtheria remains a concern globally, particularly in regions with variable immunization coverage.
    • Vaccination is the primary method for preventing diphtheria, caused by Corynebacterium diphtheria.

    Observation:

    • A fully immunized 31-year-old woman presented with cutaneous diphtheria affecting her nose and throat upon returning to Germany from Tanzania.
    • Her four-year-old son, also immunized, was found to be colonized with Corynebacterium diphtheria asymptomatically.

    Findings:

    • The case demonstrates that immunization did not prevent symptomatic cutaneous diphtheria in the mother.
    • Asymptomatic carriage of Corynebacterium diphtheria was observed in an immunized child, indicating potential for transmission.

    Implications:

    • This case underscores the importance of considering diphtheria in differential diagnoses, even in vaccinated individuals, especially after travel to endemic areas.
    • Further investigation into vaccine effectiveness and transmission dynamics in diverse settings may be warranted.

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