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Updated: Sep 5, 2025

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A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
Published on: February 28, 2015
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Colorimetric detection of RNA fragments based on associated toehold-mediated reaction and gold nanoparticles
Wantong Zhang1, Juanjuan Song1, Hongzheng Zheng1
1School of Chemistry and Chemical Engineering, Shandong University, 250100 Jinan, P. R. China. xuxw@sdu.edu.cn.
Abstract:
Herein we report a reverse transcription-free, label-free and enzyme-free colorimetric method for RNA nucleic acid fragments detection. The method can conveniently determine the presence of dual gene targets and distinguish single nucleotide polymorphism by visual observation.

