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Related Concept Videos

Endocrine Signaling01:45

Endocrine Signaling

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Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
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Intracellular Signaling Cascades01:24

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Once a ligand binds to a receptor, the signal is transmitted through the membrane and into the cytoplasm. The continuation of a signal in this manner is called signal transduction. Signal transduction only occurs with cell-surface receptors, which cannot interact with most components of the cell, such as DNA. Only internal receptors can interact directly with DNA in the nucleus to initiate protein synthesis. When a ligand binds to its receptor, conformational changes occur that affect the...
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Autocrine Signaling01:01

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Autocrine signaling is one of the many signaling mechanisms that function inside multicellular organisms to carry out intercellular communication. In this type of signaling mechanism, the same cell that secretes an extracellular signaling molecule also expresses the receptors to bind and respond to that signaling molecule.
Autocrine Signaling in Macrophages
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Related Experiment Video

Updated: Sep 5, 2025

Inducing Plasticity of Astrocytic Receptors by Manipulation of Neuronal Firing Rates
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Endocannabinoid signaling in astrocytes.

Abel Eraso-Pichot1,2, Sandrine Pouvreau1,2, Alexandre Olivera-Pinto1,2

  • 1U1215 Neurocentre Magendie, Institut national de la santé et de la recherche médicale (INSERM), Bordeaux, France.

Glia
|July 13, 2022
PubMed
Summary

This review explores how cannabinoids influence astrocytes, key brain cells. We detail cannabinoid interactions with astrocyte functions like calcium signaling, gliotransmission, metabolism, and inflammation.

Keywords:
astrocytescalciumcannabinoidsgliotransmissionmetabolismneuroinflammation

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Last Updated: Sep 5, 2025

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Area of Science:

  • Neuroscience
  • Astrocyte Biology
  • Cannabinoid Research

Background:

  • Astrocytes play increasingly recognized roles in brain function, particularly in synaptic processes.
  • Cannabinoids have demonstrated diverse interactions with astrocytes, affecting their functions and neuronal communication.
  • Recent research highlights the significance of astrocytes in neurological processes.

Conclusions:

  • Astrocytes are significant targets for cannabinoid action within the central nervous system.
  • Cannabinoid modulation of astrocytes influences fundamental brain processes, offering therapeutic potential.
  • Further research into astrocyte-cannabinoid interactions is crucial for understanding brain function and developing novel treatments.