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Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
Published on: January 11, 2020
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3D printing methods for radiological anthropomorphic phantoms.
1Research Institute, Medical University of Varna, Bulgaria.
Physics in Medicine and Biology
|July 13, 2022
Summary
Three dimensional (3D) printing offers advanced anthropomorphic phantoms for radiological applications. Fused filament fabrication (FFF) shows promise for realistic, cost-effective phantoms, though material development is key.
Area of Science:
- Medical Imaging and Radiation Oncology
- Biomedical Engineering
- Materials Science
Background:
- Three dimensional (3D) printing is increasingly used for fabricating anthropomorphic phantoms.
- Existing methods require further development in software and materials for enhanced realism and accuracy.
- There is a growing demand for high-quality phantoms that closely mimic human anatomy and tissue properties.
Purpose of the Study:
- To review and evaluate current 3D printing technologies for anthropomorphic phantom fabrication.
- To identify advancements and limitations in 3D printing methods and materials for radiological applications.
- To explore the potential of different 3D printing techniques in creating realistic and radiologically equivalent phantoms.
Main Methods:
- Review of five primary 3D printing methods: photo-curing, melted plastic deposition, paper-based printing, powder binding/melting, and bio-printing.
- Focus on polymer jetting and fused filament fabrication (FFF), also known as fused deposition modelling (FDM).
- Analysis of material properties, accuracy, speed, cost, and potential for emulating human tissues.
Main Results:
- Polymer jetting and FFF are identified as promising technologies for realistic anthropomorphic phantoms.
- Paper-based and polymer jetting methods have material limitations (e.g., contrast agents, polymerizable materials).
- FFF offers flexibility in material composition, lower cost, and suitability for large, heterogeneous phantoms despite lower speed and accuracy.
Conclusions:
- FFF technology presents a promising, cost-effective approach for creating patient-specific anthropomorphic phantoms.
- Further development in 3D printing software and materials is crucial for achieving higher accuracy and tissue emulation.
- Advancements in 3D printing hold significant potential for improving radiological applications and patient treatment adaptation.

