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Updated: Sep 4, 2025
Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations
Published on: February 2, 2024
Profile of children with cerebral palsy at a tertiary hospital in eastern Nepal
Shipra Chaudhary1, Nisha Keshary Bhatta2, Prakash Poudel2
1B P Koirala Institute of Health Sciences, Dharan, Nepal. nowshipra@gmail.com.
Insights
This study profiles Cerebral Palsy (CP) in Nepal, finding spastic quadriplegia and perinatal factors common. Improved perinatal care is crucial for preventing CP in resource-limited settings.
Area of Science:
- Pediatrics
- Neurology
- Public Health
Background:
- Cerebral Palsy (CP) data is scarce in resource-limited settings.
- Clinical presentation of CP varies globally.
- This study addresses the data gap in eastern Nepal.
Purpose of the Study:
- To describe the clinical profile of children with Cerebral Palsy (CP).
- To identify etiological factors and comorbidities in CP.
- To understand current management and educational support for CP patients in eastern Nepal.
Main Methods:
- Hospital-based cross-sectional descriptive study.
- Inclusion criteria: Children aged 6 months to 15 years presenting with CP.
- Data collected: Clinical details, etiology, comorbidities, treatments, and education.
Main Results:
- 110 children with CP were studied; 74.54% were male.
- Spastic quadriplegia (44.44%) and GMFCS Level III (41.81%) were most common.
- Perinatal factors (64.54%) and postnatal infections (25.45%) were leading causes; intellectual disability (71.81%) and epilepsy (66.36%) were frequent comorbidities.
Conclusions:
- The study provides a profile of CP in eastern Nepal.
- High prevalence of perinatal complications and postnatal infections highlights the need for improved perinatal and neonatal care.
- Urgent improvements in healthcare delivery systems are recommended to mitigate CP causes.
Background:
The clinical spectrum of Cerebral palsy (CP) can differ in various places depending upon knowledge of the people and resources for prevention, diagnosis and management. Although studied extensively in high-resource countries, adequate data related to CP from resource-constraint settings are lacking. This study aims to describe the profile of children with CP at a tertiary care center in eastern Nepal.
Methods:
This was a hospital-based cross-sectional descriptive study done from 2017 to 2018. Children 6 months to 15 years who presented with CP were enrolled and their clinical details recorded and described.
Results:
Amongst 110 children with CP, 74.54% were male. Majority (76.36%) were 5 years or below with the median age being 3(2.00-4.75) years. Children with spastic quadriplegia (44.44%) and Gross Motor Function Classification System level III (41.81%) were most common. Etiologically, perinatal factors (64.54%) like perinatal asphyxia (35.45%) and prematurity (20.90%) and postnatal infections (25.45%) were common. The common comorbidities were intellectual disability (71.81%) and epilepsy (66.36%). The main treatment modalities were: antiepileptics (59.09%) and centre-based physiotherapy sessions (35.45%). School education was provided in 23.07% with special education in 11.53%.
Conclusions:
This study describes the profile of CP at our centre in eastern Nepal. Predominance of perinatal complications and postnatal infections points towards the urgent need to further improve the perinatal and neonatal health care delivery system and practices.
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