Triple phase CT in evaluating indeterminate focal liver lesion

Indeterminate focal liver lesions (FLLs) detected through ultrasonography or single-phase imaging present a diagnostic challenge due to their varied management depending on whether they are benign or malignant. Therefore, it is of interest to evaluate the diagnostic performance of triple-phase multidetector computed tomography (MDCT) in characterizing these lesions by assessing dynamic contrast enhancement across arterial, portal venous and delayed phases. Results showed that triple-phase CT accurately differentiated benign from malignant lesions, with vascular and enhancement patterns providing key diagnostic insights. Malignant lesions exhibited distinct features, including portal venous hypoenhancement and late-phase washout. Thus, we show the high accuracy of triple-phase CT for managing indeterminate FLLs, supporting better clinical decision-making.