Related Experiment Video

Updated: Sep 4, 2025

Conducting Respiratory Oscillometry in an Outpatient Setting
14:49

Conducting Respiratory Oscillometry in an Outpatient Setting

Published on: April 8, 2022

7.4K

Reference values of impulse oscillometry (IOS) for healthy Chinese children aged 4-17 years

Jinhong Wu1, Hao Zhang2, Yongsheng Shi3

  • 1Department of Respiratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.

Respiratory Research
|July 13, 2022
PubMed

Insights

This study establishes predicted lung function values using impulse oscillometry (IOS) for healthy Chinese children aged 4-17. The derived reference equations are tailored for this population, improving lung function assessment accuracy.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Physiology
  • Biomedical Engineering

Background:

  • Accurate pulmonary function assessment in children is crucial for diagnosing and managing respiratory conditions.
  • Existing reference equations for lung function tests may not accurately reflect the physiological characteristics of diverse pediatric populations.
  • Impulse oscillometry (IOS) offers a non-invasive method for evaluating respiratory mechanics in children.

Purpose of the Study:

  • To establish normative predicted values for impulse oscillometry (IOS) parameters in healthy Chinese children aged 4 to 17 years.
  • To develop regression equations for IOS parameters based on anthropometric data (height, age, weight) specific to the Chinese pediatric population.
  • To compare the suitability of the newly derived reference equations with existing ones for Chinese children.

Main Methods:

  • A cross-sectional study involving 6270 healthy Chinese children aged 4-17 years.
  • Pulmonary function was assessed using the Master Screen IOS device, measuring respiratory impedance (Zrs), resonant frequency (Fres), respiratory system resistance (Rrs), and respiratory system reactance (Xrs).
  • Stepwise multivariate regression analysis was employed to establish predictive equations for IOS parameters based on sex, age, height, and weight.

Main Results:

  • Significant differences in IOS parameters were observed across different age groups in both sexes (P < 0.05).
  • IOS parameters demonstrated strong correlations with height, age, and weight, with height being the most influential factor.
  • Increasing age and height were associated with decreased Z5, R5, R20, R5-R20, and Fres, and increased X5.
  • A novel reference equation for children's IOS parameters was developed using height, age, and weight.

Conclusions:

  • The study successfully established reference values for impulse oscillometry parameters in healthy Chinese children.
  • The newly developed predictive equation is more appropriate for assessing lung function in Chinese children compared to existing international reference equations.
  • These findings provide a valuable tool for more accurate interpretation of IOS results in pediatric respiratory health evaluations in China.
Abstract

Keywords:
ChildImpulse oscillometryNormal predicted valuePulmonary function test

More Related Videos

Measuring Cardiac Autonomic Nervous System ANS Activity in Children09:45

Measuring Cardiac Autonomic Nervous System ANS Activity in Children

Published on: April 29, 2013

21.1K
Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults06:11

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

5.7K

Related Concept Videos

Special considerations while measuring pulse01:13

Special considerations while measuring pulse

Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
651
Special considerations while measuring oxygen saturation01:19

Special considerations while measuring oxygen saturation

Assessing respiratory rate concurrently with pulse measurement is fundamental to patient care, providing valuable insights into the patient's respiratory function. The normal breathing rate for an adult usually falls within a normal range of 12 to 20 breaths per minute. Abnormal respiratory rates can signal underlying health conditions or the need for immediate intervention.
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
695
Guidelines For Measuring Vital Signs01:19

Guidelines For Measuring Vital Signs

Following these guidelines can help nurses accurately measure vital signs, assess changes in patient conditions, and provide timely treatment when necessary. Adhering closely to the guidelines ensures the accuracy and reliability of the results.
Before taking a patient's vital signs, a nurse would consider and assess the patient's comfort level and ensure appropriate equipment is available.
1.9K
Pulse Oximetry01:24

Pulse Oximetry

Pulse oximetry, or SpO2, is a non-invasive method for continuously monitoring arterial oxygen saturation (SaO2). This procedure involves attaching a probe or sensor to the patient's fingertip, forehead, earlobe, or nose bridge. The sensor works by detecting changes in oxygen saturation levels through light signals generated by the oximeter and reflected by the pulsing blood under the probe.
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
398
Pulse amplitude and quality01:17

Pulse amplitude and quality

Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
2.1K