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Aptasensor Based on Microfluidic for Foodborne Pathogenic Bacteria and Virus Detection: A Review
Indrajit Patra1, Mustafa M Kadhim2, Marwan Mahmood Saleh3
1An Independent Researcher, Ex Research Scholar at National Institute of Technology Durgapur, Durgapur, India.
Critical Reviews in Analytical Chemistry
|July 14, 2022
Summary
New aptasensor technology using microfluidics offers sensitive and selective detection of foodborne pathogens. This review explores these advancements for improved food safety screening.
Area of Science:
- Food safety
- Biosensing
- Microfluidics
Background:
- Foodborne pathogenic bacteria and viruses pose significant risks to public health.
- Current detection methods often lack the required sensitivity and selectivity for small pathogens.
- On-site detection platforms are crucial for effective food safety management.
Purpose of the Study:
- To review recent advancements in aptasensor technology based on microfluidics for detecting foodborne pathogens.
- To discuss the working strategies, benefits, and drawbacks of these microfluidic aptasensing approaches.
Main Methods:
- Integration of microfluidics with analytical techniques (electrochemical, optical, colorimetric).
- Utilization of aptamers as selective bioreceptors within microfluidic systems.
- Leveraging smartphone technology for enhanced data transfer and computational power.
Main Results:
- Microfluidic aptasensors demonstrate potential for sensitive, selective, portable, and affordable pathogen detection.
- Integration with smartphones enhances data analysis and accessibility.
- These systems offer improved on-site detection capabilities for food safety.
Conclusions:
- Microfluidic aptasensors represent a promising technology for the screening of foodborne pathogenic bacteria and viruses.
- Further development can lead to more robust and widely applicable food safety solutions.
- This review provides a comprehensive overview of the current landscape and future directions.
