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Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
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Hepatic Function Predictive Value of Hepatic Venous Waveform versus Portal Vein Velocity in Liver Cirrhosis

Chidiogo Chukwunweike Onwuka1, Olusola Comfort Famurewa2, Olusegun Adekanle3

  • 1Department of Radiology, ABUAD Multi System Hospital, Ado-Ekiti, Nigeria.

Journal of Medical Ultrasound
|July 14, 2022
PubMed

Insights

Hepatic vein waveform (HVW) abnormalities are better predictors of liver dysfunction in liver cirrhosis (LC) patients than portal vein velocity. HVW changes can aid in assessing liver function alongside the Child-Turcotte-Pugh (CTP) score.

Area of Science:

  • Medical Imaging
  • Hepatology
  • Diagnostic Ultrasound

Background:

  • Liver cirrhosis (LC) is a significant health concern.
  • Assessing hepatic function in LC patients is crucial for management.
  • Doppler ultrasound parameters like hepatic vein waveform (HVW) and portal vein velocity (PVV) are investigated for diagnostic value.

Purpose of the Study:

  • To assess hepatic vein waveform (HVW) and mean maximum portal vein velocity (MM-PVV) in liver cirrhosis (LC) patients.
  • To compare HVW and MM-PVV between LC patients and healthy controls.
  • To correlate HVW and MM-PVV with liver function using the Child-Turcotte-Pugh (CTP) score to determine predictive value.

Main Methods:

  • Sixty LC patients and 60 healthy controls were enrolled.
  • Doppler ultrasound was used to evaluate HVW and MM-PVV.
  • HVW was categorized as triphasic, biphasic, or monophasic.

Main Results:

  • Abnormal HVW was observed in 76.7% of LC patients versus 0% in controls (P < 0.001).
  • MM-PVV was significantly lower in LC patients (22.8 cm/s) compared to controls (33.6 cm/s) (P < 0.001).
  • HVW abnormality positively correlated with CTP score (r = 0.283, P = 0.029), while MM-PVV did not (r = -0.124, P = 0.346).

Conclusions:

  • Abnormalities in hepatic vein waveform (HVW) are more predictive of hepatic dysfunction in liver cirrhosis than changes in portal vein velocity.
  • HVW patterns can serve as a valuable adjunct to the Child-Turcotte-Pugh (CTP) classification for assessing liver function.
Abstract

Keywords:
Hepatic vein waveformliver cirrhosisportal vein velocityultrasound

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