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Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2

Irene P Chen1, James E Longbotham2, Sarah McMahon1

  • 1Gladstone Institutes, San Francisco, CA 94158, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA.

Cell Reports
|July 15, 2022
PubMed

Keywords:
BET inhibitorsBET proteinsBRD2BRD3BRD4COVID-19CP: MicrobiologySARS-CoV-2antiviral responsehistone mimeticviral replication

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