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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Protocol for Home-Based Solution for Remote Atrial Fibrillation Screening to Prevent Recurrence Stroke (HUA-TUO AF

Chun Ka Wong1, Jo Jo Hai1, Yuk-Ming Lau1

  • 1Cardiology Division, Department of Medicine, University of Hong Kong, Hong Kong, Hong Kong.

BMJ Open
|July 15, 2022
PubMed

Insights

This study investigates long-term home-based ECG monitoring for detecting atrial fibrillation (AF) after stroke. Early AF detection aims to prevent recurrent strokes, improving patient outcomes.

Area of Science:

  • Cardiology and Neurology
  • Medical Technology and Digital Health

Background:

  • International guidelines recommend ECG monitoring post-ischaemic stroke to detect atrial fibrillation (AF) and prevent recurrence.
  • Optimal AF detection strategies and subsequent management for stroke prevention require further investigation.

Purpose of the Study:

  • To explore the efficacy of long-term, home-based ECG monitoring for AF detection in stroke patients.
  • To assess the impact of this strategy on preventing stroke recurrence over a 24-month period.

Main Methods:

  • Prospective, randomized, open-label trial with blinded endpoint adjudication.
  • Patients with a history of ischaemic stroke stratified by time since event (<1, 1-3, >3 years).
  • Intervention group uses a handheld ECG device and smartphone app for daily/symptomatic recording; data analyzed by AI. Control group receives standard care.

Main Results:

  • Primary endpoint: Time to first AF detection at 24 months.
  • Secondary endpoints: Recurrent stroke/TIA, anticoagulation initiation, heart failure hospitalization, cardiovascular death, all-cause death.

Conclusions:

  • The study aims to establish the effectiveness of a novel home-based AF screening system.
  • Findings will inform clinical practice regarding AF detection and stroke prevention strategies.
Abstract

Keywords:
Adult cardiologyStrokeTelemedicine

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