An integrated nanoflower-like MoS₂@CuCo₂O₄ heterostructure for boosting electrochemical glucose sensing in beverage

Excessive glucose in food poses a non-negligible threat to its inherent quality and human health, which makes it imperative to develop a highly sensitive sensor for real-time glucose detection. In this work, an integrated electrochemical glucose sensor based on a nanoflower-like MoS₂@CuCo₂O₄ heterostructure was carefully constructed. Under optimal conditions, the as-fabricated sensor exhibited a high sensitivity of 1,303 μA mM^-1 cm^-2 over a wide range of 0.5-393.0 μmol/L, accompanied by a low determination limit (0.5 μmol/L) and short response time (2.1 s). The favorable sensing performance of the MoS₂@CuCo₂O₄ nanocomposite-modified electrode in electrochemical analyses was attributed to the introduction of unique nanoflower-like heterostructure and the synergistic effects between MoS₂ and CuCo₂O₄. Furthermore, the satisfactory applicability of this sensor in beverages was confirmed. These results demonstrate that the MoS₂@CuCo₂O₄/GCE may be a promising platform for sensitive monitoring of glucose content in food samples.