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Diarrhea is characterized by the occurrence of frequent, watery bowel movements. Various factors can trigger diarrhea, including viral or bacterial infections, foodborne illnesses, side effects from certain medications, and underlying digestive disorders. If not adequately managed, diarrhea can lead to complications such as dehydration, electrolyte imbalances, and nutrient deficiencies. Severe diarrhea can lead to significant weight loss, malnutrition, and weakened immune function.
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Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
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Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
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Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
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Herbal anthelmintic agents: a narrative review.

Manjusa Adak1, Pradeep Kumar1

  • 1Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Ghudda, Bathinda, Punjab 151401, India.

Journal of Traditional Chinese Medicine = Chung I Tsa Chih Ying Wen Pan
|July 18, 2022
PubMed
Summary
This summary is machine-generated.

This review compiles plant-derived anthelmintics, crucial for combating neglected tropical diseases (NTDs) caused by parasitic worms. It highlights plant metabolites with significant anthelmintic activity, offering potential for new drug development.

Keywords:
anthelminticsbiological productshelminthiasishelminths

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Area of Science:

  • Ethnobotany
  • Pharmacology
  • Tropical Medicine

Background:

  • Helminth infections, classified as neglected tropical diseases (NTDs), affect approximately two billion people globally, causing chronic and potentially fatal conditions.
  • Plants have historically served as a source of anthelmintic agents for treating parasitic worm infections.

Purpose of the Study:

  • To compile and review plant-derived sources of anthelmintic drugs.
  • To summarize research on the anthelmintic activities of plants published since 2005.

Main Methods:

  • A comprehensive literature search was conducted using electronic databases: Scopus, Google Scholar, Web of Science, and PubMed.
  • The review focused on studies published from 2005 onwards, identifying plants with documented anthelmintic activity.

Main Results:

  • The literature survey revealed that various plant secondary metabolites possess anthelmintic properties.
  • Key active compounds identified include terpenes, glycosides, saponins, flavonoids, tannins, and alkaloids.

Conclusions:

  • Plant-derived compounds, particularly specific secondary metabolites, demonstrate significant anthelmintic potential.
  • This compilation serves as a valuable resource for researchers investigating novel anthelmintic drug discovery from botanical sources.