Recent modalities in treatment of telogen effluvium: Comparative study

Area of Science:

• Dermatology
• Hair Restoration Science

Background:

• Telogen effluvium is a common cause of diffuse, non-scarring hair loss.
• While often reversible by addressing underlying causes, therapeutic options are needed.
• Current management requires effective and patient-friendly treatment modalities.

Purpose of the Study:

• To compare the efficacy of a single botulinum toxin A injection versus multiple sessions of multivitamins mesotherapy for treating telogen effluvium.
• To evaluate hair parameters, including terminal hair count and follicular units, as indicators of treatment success.
• To assess the safety and tolerability of both treatment approaches.

Main Methods:

• A randomized clinical trial involving 24 patients diagnosed with telogen effluvium.
• Patients were divided into two groups: Group I (12 patients) received one botulinum toxin A injection, and Group II (12 patients) underwent multiple multivitamins mesotherapy sessions.
• Hair parameters were assessed to quantify treatment outcomes.

Main Results:

• Both botulinum toxin A and multivitamins mesotherapy demonstrated effectiveness in treating telogen effluvium.
• Improvements were observed in key hair parameters, such as increased terminal hair and multiple follicular units.
• Both treatments exhibited minimal and well-tolerated side effects.

Conclusions:

• Single-session botulinum toxin A injections and multiple multivitamins mesotherapy sessions are effective treatments for telogen effluvium.
• Both modalities show comparable success rates in improving hair parameters.
• A single session of botulinum toxin A is recommended as a more advantageous treatment option due to its convenience compared to multiple mesotherapy sessions.