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Model of Osteomyelitis in Rats

E N Ovchinnikov¹, O V Dyuryagina¹, M V Stogov²

¹G. A. Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Kurgan, Russia.

Bulletin of Experimental Biology and Medicine

|July 19, 2022

Abstract:

We developed a rat model of chronic osteomyelitis of the femur caused by Staphylococcus aureus. The clinical, histomorphological, and laboratory signs were compared in rats with osteomyelitis (infected) and control animals receiving saline. On day 21 after infection, clinical, histomorphological, and laboratory signs of chronic osteomyelitis were found in experimental rats.

Keywords:

Staphylococcus aureus experimental model femur osteomyelitis rats

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