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Related Experiment Video

Updated: Sep 4, 2025

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Published on: March 13, 2019

Chemically Driven Rotatory Molecular Machines.

Anirban Mondal¹, Ryojun Toyoda^1,2, Romain Costil¹

¹Stratingh Institute for Chemistry University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.

Angewandte Chemie (International Ed. in English)

|July 19, 2022

Summary

Chemically controlled molecular machines offer new ways to create adaptive materials. This review explores atropisomers that rotate chemically, advancing molecular switches, rotors, and motors.

Keywords:

Chemically Driven Molecular Machines Molecular Motors Molecular Rotors Molecular Switches

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Area of Science:

Molecular machines
Supramolecular chemistry
Materials science

Background:

Molecular machines are key to developing responsive materials by emulating biological systems.
Significant advances have been made in light-induced molecular rotation.
Achieving unidirectional rotation via chemical conversion remains a challenge.

Purpose of the Study:

To review approaches for designing and synthesizing atropisomers capable of chemical-induced rotation.
To categorize these molecules as switches, rotors, motors, or autonomous motors based on their response.
To discuss future perspectives and challenges in sophisticated molecular machine development.

Main Methods:

Overview of design and synthesis strategies for atropisomers.
Analysis of dynamic properties under chemical stimuli.
Categorization based on molecular response mechanisms.

Main Results:

Presentation of various atropisomers that exhibit controlled switching or rotation.
Classification of molecules into functional categories: switches, rotors, motors, and autonomous motors.
Identification of key chemical stimuli for inducing molecular motion.

Conclusions:

Chemically driven molecular machines represent a significant advancement.
Atropisomers offer a viable platform for controlled molecular motion.
Further research is needed to build more complex and sophisticated molecular machines.