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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Related Experiment Video

Updated: Sep 4, 2025

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
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Hypopyon after Periocular Corticosteroid Injection: A Case Series.

Fangting Li1,2, Qin Zhang1,2

  • 1Department of Ophthalmology, Peking University People's Hospital, Eye Diseases and Optometry Institute, Beijing, China.

Ocular Immunology and Inflammation
|July 19, 2022
PubMed
Summary

Periorbital corticosteroid injections can lead to hypopyon, a rare complication. Prompt treatment with topical steroids and antivirals is crucial for managing associated herpes simplex virus (HSV) keratitis.

Keywords:
Anti-viruscorticosteroidherpes simplex virusherpes simplex virus keratitishypopyonperiocular injection

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Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Periorbital corticosteroid injections are common treatments for various ocular conditions.
  • Hypopyon is a rare but serious potential complication following such injections.

Purpose of the Study:

  • To describe a case series of hypopyon following periorbital corticosteroid injection.
  • To investigate the clinical presentation and management of hypopyon in this context.

Main Methods:

  • Retrospective, observational case series.
  • Analysis of three patients who developed hypopyon after periorbital corticosteroid injection.

Main Results:

  • All three patients presented with hypopyon after periocular corticosteroid injection.
  • Diagnoses included herpes simplex virus (HSV) stromal keratitis or endotheliitis.
  • Successful treatment involved topical steroids and systemic/topical antiviral therapy.

Conclusions:

  • Periocular corticosteroid injection is not recommended in cases of HSV keratitis.
  • Topical corticosteroids are the preferred treatment for HSV stromal keratitis and endotheliitis.