Mesenteric panniculitis is associated with cardiovascular risk-factors: A case-control study
Hagai Schweistein1, Yoav Weintraub2, Tzipi Hornik-Lurie3
1Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel; Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv, Israel.
Summary
Patients with mesenteric panniculitis exhibit a higher prevalence of cardiovascular risk factors, including dyslipidemia, hypertension, and obesity. This suggests a potential link between mesenteric panniculitis and metabolic conditions.
Area of Science:
- Gastroenterology
- Cardiology
- Radiology
Background:
- Mesenteric panniculitis is a rare condition affecting the mesentery.
- The association between cardiovascular risk factors and mesenteric panniculitis is not well-established.
Purpose of the Study:
- To evaluate the prevalence of cardiovascular risk factors in patients diagnosed with mesenteric panniculitis.
- To determine if cardiovascular risk factors are associated with mesenteric panniculitis.
Main Methods:
- Retrospective, matched case-control study.
- Inclusion criteria: patients diagnosed with mesenteric panniculitis via CT scan (2014-2019).
- Exclusion criteria: active malignancy, IBD, significant intra-abdominal morbidity.
Main Results:
- Compared to controls, patients with mesenteric panniculitis showed higher rates of dyslipidemia (77.5%), hypertension (52.4%), obesity (60.4%), and nonalcoholic fatty liver disease (42.2%).
- Dyslipidemia, obesity, and nonalcoholic fatty liver disease were identified as independent predictors for mesenteric panniculitis.
- These associations remained significant when compared to both hospitalized controls and the general population.
Conclusions:
- Mesenteric panniculitis is associated with a greater burden of cardiovascular risk factors.
- This finding highlights the clinical significance of mesenteric panniculitis and its potential role in metabolic morbidity.
- Further research is warranted to explore this association.
Keywords:
DyslipidemiaMesenteric lipodystrophyMesenteric panniculitisMetabolic syndromeNonalcoholic fatty liver diseaseObesitySclerosing mesenteritisMore Related Videos
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