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Transepithelial photorefractive keratectomy: a prospective randomized comparative study between the two-step and the
Mahmoud Abdel-Radi1, Mohamed Shehata2, Magdi Mohammad Mostafa2
1Department of Ophthalmology, Assiut University, Assiut, Egypt. mahmoudradi@aun.edu.eg.
Eye (London, England)
|July 21, 2022
Summary
Single-step transepithelial photorefractive keratectomy (PRK) offers superior outcomes for myopia correction compared to the two-step PTK-PRK method. This approach results in faster visual recovery and reduced post-operative pain.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Corneal Surgery
Background:
- Transepithelial photorefractive keratectomy (PRK) is a common procedure for correcting refractive errors.
- Two variations exist: two-step PTK-PRK and single-step PRK.
- Comparing their efficacy and outcomes is crucial for optimizing patient care.
Purpose of the Study:
- To compare the six-month outcomes of two-step transepithelial PTK-PRK and single-step transepithelial PRK.
- To evaluate visual acuity, refractive outcomes, and healing parameters.
- To determine the optimal transepithelial PRK technique for myopia and myopic astigmatism.
Main Methods:
- A prospective randomized study involving 100 eyes of 50 patients.
- Patients were divided into two groups: two-step PTK-PRK (50 eyes) and single-step PRK (50 eyes).
- Primary outcomes included visual acuity and manifest refraction; secondary outcomes were epithelial healing, pain, and haze.
Main Results:
- Single-step PRK demonstrated significantly better uncorrected distance visual acuity at all follow-up points.
- Manifest refraction outcomes favored single-step PRK.
- Epithelial healing was faster, and post-operative pain scores were lower with single-step PRK.
Conclusions:
- Both transepithelial PRK techniques effectively correct mild to moderate myopia and myopic astigmatism.
- Single-step transepithelial PRK provides superior results, including faster visual recovery, better refractive outcomes, and reduced pain.
- This study supports single-step transepithelial PRK as a preferred method.
