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Updated: Sep 4, 2025
04:01
Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis
Published on: June 14, 2024
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Crohn's Disease Presenting as Metabolic Myopathy: A Case Report
Sabu Kunnathuparambil George1, Neena Baby2, Prasanth Varghese1
1Department of Neurology, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India.
Neurology India
|July 22, 2022
Summary
Crohn
Area of Science:
- Internal Medicine
- Neurology
- Gastroenterology
Background:
- Myopathies can manifest as initial symptoms in various systemic diseases.
- Crohn's disease rarely presents with myopathy as the primary symptom.
Observation:
- A 20-year-old female presented with painful proximal myopathy, malnutrition, anemia, hypoalbuminemia, low vitamin D, and elevated creatine phosphokinase.
- Initial investigations suggested osteomalacic myopathy, but malabsorption workup was negative.
Findings:
- Colonoscopic biopsy revealed noncaseating granulomatous inflammation, confirming Crohn's disease.
- The patient recovered fully with supplementary therapy and specific treatment for Crohn's disease.
Implications:
- This case highlights the importance of considering systemic diseases like Crohn's in unexplained myopathies.
- A systematic diagnostic approach is crucial for identifying myopathy associated with systemic illness.
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