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POSTINFECTIOUS NONPARANEOPLASTIC AUTOIMMUNE RETINOPATHY IN THE PEDIATRIC AGE GROUP: A HIGH INDEX OF SUSPICION,

Neena R1, Ashapurna Borgohain2, Giridhar Anantharaman2

  • 1Paediatric Ophthalmology, Strabismus and Neuro-ophthalmology.

Retinal Cases & Brief Reports
|August 9, 2023
PubMed

Insights

Early diagnosis and treatment of nonparaneoplastic autoimmune retinopathy in a child led to significant vision recovery. Multimodal imaging aided diagnosis in this pediatric vision loss case.

Area of Science:

  • Ophthalmology
  • Pediatric Neurology
  • Autoimmune Diseases

Background:

  • Autoimmune retinopathy can cause severe vision loss.
  • Pediatric cases are rare and often present with non-specific symptoms.

Purpose of the Study:

  • To describe a pediatric case of nonparaneoplastic autoimmune retinopathy.
  • To emphasize the importance of early diagnosis and prompt treatment for visual recovery.

Main Methods:

  • Retrospective case report.
  • Clinical examination and multimodal imaging (including optical coherence tomography).
  • Treatment with intravenous methylprednisolone and oral steroids.

Main Results:

  • A 5-year-old girl experienced sudden bilateral vision loss.
  • Diagnosis of nonparaneoplastic autoimmune retinopathy was confirmed.
  • Excellent visual acuity improvement and retinal layer restoration occurred within 3 months of treatment.

Conclusions:

  • Nonparaneoplastic autoimmune retinopathy should be suspected in children with sudden vision loss.
  • Multimodal imaging is crucial for diagnosis.
  • Early intervention can lead to significant visual recovery, even with negative antibody tests.
Abstract

Keywords:
fundus autofluorescence (FAF)nonparaneoplastic autoimmune retinopathy (npAIR)optical coherence tomography (OCT)

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