The present and the future of protein biosensor engineering

Colin Jackson1, Alisha Anderson2, Kirill Alexandrov3

  • 1Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia; Australian Research Council Centre of Excellence in Synthetic Biology, Australian National University, Canberra, ACT 2601, Australia; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, Australian National University, Canberra, ACT 2601, Australia.

Summary

Researchers are developing advanced protein biosensors for cell biology and clinical diagnostics. By engineering artificial receptors and Chemically Induced Dimerisation (CID) systems, they create analyte-operated switches for improved biosensing applications.