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Updated: Sep 3, 2025

Dual-Color Fluorescence Cross-Correlation Spectroscopy to Study Protein-Protein Interaction and Protein Dynamics in Live Cells
Published on: December 11, 2021
Continuing progress in the field of two-dimensional correlation spectroscopy (2D-COS), part I. Yesterday and today
Yeonju Park1, Sila Jin1, Isao Noda2
1Kangwon Radiation Convergence Research Support Center, Kangwon National University, Chuncheon 24341, South Korea.
Abstract:
This comprehensive survey review, as the first of three parts, compiles past developments and early concepts of two-dimensional correlation spectroscopy (2D-COS) and subsequent evolution, as well as its early applications in various fields for the last 35 years. It covers past review articles, books, proceedings, and numerous research papers published on 2D-COS. 2D-COS continues to evolve and grow with new significant developments and versatile applications in diverse scientific fields. The healthy, vigorous, and diverse progress of 2D-COS studies in many fields confirms that it is well accepted as a powerful analytical technique to provide the in-depth understanding of systems of interest.
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