Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Role of Hippocampus in Memory

Role of Hippocampus in Memory

The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...

Olfaction

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...

Hearing

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.

Auditory Pathway

Auditory Pathway

Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...

The Cochlea

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.

Functional Brain Systems: Limbic System

Functional Brain Systems: Limbic System

The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evidence for a Transient State of Auditory Hypersensitivity During Initial Onset of Tinnitus: IDAEP Changes Between Acute and Chronic Tinnitus.

Trends in hearing·2026

Same author

Tinnitus and tinnitus disorder: Genetic, neurobiological, and clinical differentiation.

iScience·2026

Same author

Immediate to longer-term neurophysiological impact of acute neural network disruption.

medRxiv : the preprint server for health sciences·2026

Same author

Sound hypersensitivity phenotypes and sound hypersensitivity disorder.

Neuroscience and biobehavioral reviews·2026

Same author

Testing and tracking in the UK: A dynamic causal modelling study.

Wellcome open research·2026

Same author

Stimulus statistical context sensitivity of deviant responses to auditory intensity changes.

Scientific reports·2026

Same journal

Deletion of Fbxo25 causes excessive repetitive behavior, impaired recognition memory, reduced dendritic complexity, and aberrant protein expression in mice.

Progress in neurobiology·2026

Same journal

Neuropsychiatric Disease Mechanisms and Interventions. from 22q11.2 Deletion Syndrome Experimental Studies.

Progress in neurobiology·2026

Same journal

REM sleep as a dummy-model of the world: A theoretical framework.

Progress in neurobiology·2026

Same journal

CA3 transiently modulates spatial representation in CA1.

Progress in neurobiology·2026

Same journal

Love, death, and oxytocin: In memory of Larry Young.

Progress in neurobiology·2026

Same journal

Assessing peripheral oxytocin and cortisol levels and epigenetic variations of oxytocin receptor and glucocorticoid receptor genes in school-aged preterm-born children.

Progress in neurobiology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Sep 3, 2025

Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue

Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue

Published on: October 21, 2021

The hearing hippocampus.

Alexander J Billig¹, Meher Lad², William Sedley²

¹UCL Ear Institute, University College London, London, UK.

Progress in Neurobiology

|July 23, 2022

Summary

This summary is machine-generated.

The hippocampus processes auditory information for memory and perception beyond spatial tasks. Understanding these sound-hippocampus interactions may aid cognition and dementia research.

Keywords:

Auditory Auditory cognition Hearing Hippocampus Medial temporal lobe Perception Sound

More Related Videos

Horizontal Hippocampal Slices of the Mouse Brain

Horizontal Hippocampal Slices of the Mouse Brain

Published on: September 22, 2020

Recording Spatially Restricted Oscillations in the Hippocampus of Behaving Mice

Recording Spatially Restricted Oscillations in the Hippocampus of Behaving Mice

Published on: July 1, 2018

Related Experiment Videos

Last Updated: Sep 3, 2025

Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue

Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue

Published on: October 21, 2021

Horizontal Hippocampal Slices of the Mouse Brain

Horizontal Hippocampal Slices of the Mouse Brain

Published on: September 22, 2020

Recording Spatially Restricted Oscillations in the Hippocampus of Behaving Mice

Recording Spatially Restricted Oscillations in the Hippocampus of Behaving Mice

Published on: July 1, 2018

Area of Science:

Neuroscience
Auditory Cognition
Memory Research

Background:

The hippocampus is crucial for spatial and episodic memory.
Wider roles in perception and relational processing are suggested.
Auditory processing networks beyond the auditory cortex are under investigation.

Purpose of the Study:

To review the hippocampus's role in processing auditory information.
To explore how sound shapes the hippocampus.
To understand the broader cognitive functions of the hippocampus.

Main Methods:

Review of imaging, recording, and lesion studies.
Examination across species from rodents to humans.
Analysis of hippocampal responses to passive and active sound exposure and learning.

Main Results:

A hierarchy of hippocampal responses to sound exists.
Hippocampal connectivity supports auditory information tracking and manipulation.
Functional and structural changes correlate with auditory experience.

Conclusions:

Hippocampal-auditory interactions support broad perceptual and cognitive functions.
These interactions extend beyond spatial and episodic memory.
Further research could lead to cognitive enhancement and dementia interventions.