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The effect of natural growth on chin point deviation in patients with unilateral craniofacial microsomia: A
Ruben W Renkema1, Irene van Beelen1, Maarten J Koudstaal1
1The Dutch Craniofacial Center, Department of Oral and Maxillofacial Surgery, Erasmus University Medical Center, Sophia's Children's Hospital Rotterdam, the Netherlands.
Insights
Craniofacial microsomia (CFM) in children appears to be a non-progressive disorder. Chin point deviation, a key indicator of mandibular asymmetry, did not significantly change with age in patients with unilateral CFM.
Area of Science:
- Craniofacial Surgery
- Pediatric Plastic Surgery
- Orthodontics
Background:
- Unilateral craniofacial microsomia (CFM) is a congenital condition characterized by asymmetric facial development.
- Mandibular asymmetry, specifically chin point deviation, is a common feature of CFM.
- Understanding the progressive nature of CFM is crucial for treatment planning.
Purpose of the Study:
- To investigate the potential progressiveness of mandibular asymmetry in pediatric patients with unilateral craniofacial microsomia (CFM).
- To identify factors influencing chin point deviation over time in these patients.
Main Methods:
- Retrospective analysis of 110 pediatric patients with unilateral CFM.
- Measurement of chin point deviation from clinical photographs.
- Statistical analysis using Jonckheere-Terpstra test and linear mixed models to assess changes with growth and correlation with Pruzansky-Kaban and soft tissue scores.
Main Results:
- No statistically significant changes in chin point deviation were observed during natural growth (p = 0.74).
- A significant correlation was found between chin point deviation and both the Pruzansky-Kaban score (p ≤ 0.001) and soft tissue score (p ≤ 0.001).
Conclusions:
- The findings suggest that unilateral craniofacial microsomia (CFM) may be a non-progressive condition.
- Chin point deviation in CFM patients does not appear to worsen with age, although severity correlates with specific clinical scoring systems.
Abstract:
This study aimed to investigate the potential progressiveness of mandibular asymmetry and to study factors that influence chin point deviation in patients with unilateral craniofacial microsomia (CFM). Paediatric patients with unilateral CFM with available radiologic imaging and medical photographs were included. Chin point deviation was measured on clinical photographs. A Jonckheere-Terpstra test and linear mixed model for repeated measurements assessed the relation of chin point deviation on natural growth, Pruzansky-Kaban score, and soft tissue score. A total of 110 patients were included. The linear mixed model showed no statistically significant changes of chin point deviation during growth (effect estimate -0.006°, 95% CI -0.04° to -0.03°, p = 0.74). A statistical significant relation between both the Pruzansky-Kaban and soft tissue score on chin point deviation was found (effect estimate -5.10°, 95% CI -6.45° to -3.75°, p ≤ 0.001 and effect estimate -3.42°, CI -5.86° to -0.98°, p ≤ 0.001, respectively). Within the limitations of the study it seems that craniofacial microsomia may be a non-progressive disorder, because chin point deviation did not change over time.

