Related Experiment Video For COVID-19
Updated: Sep 3, 2025

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Obsessive compulsive disorder as a presenting symptom of COVID-19: A case-series from Iran
Mahsa Owji1, Abdorreza Naser Moghadasi1, Faezeh Gholamian2
1Multiple Sclerosis Research Center, Neuroscience institute, Tehran University of Medical Sciences, Tehran, Iran.
Background:
Coronavirus disease 2019 (COVID-19) involves different organs and clinical presentations varying from respiratory symptoms to gastrointestinal symptoms and neurological symptoms. Another group of symptoms are psychiatric symptoms and according to a study, 53.8% of participants reported various degrees of these symptoms.
Case Presentation:
In this study, we presented six cases with sudden onset OCD or exacerbation of the previously controlled OCD concomitant with COVID-19 symptoms.
Result:
Obsessive compulsive symptoms can be the presenting manifestation of COVID-19.
Conclusion:
The neuropsychiatric manifestations may be resulted from central nervous system (CNS) infiltration, and dysregulation of inflammatory factors autoimmune responses.
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