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Resistance Training Recommendations for Children and Adolescents With Cystic Fibrosis-Related Diabetes
Clifton J Holmes1, Andrea Granados2
1Program in Physical Therapy, Washington University of Medicine, St. Louis, Missouri.
Insights
Resistance training may benefit children and adolescents with cystic fibrosis (CF) and CF-related diabetes (CFRD). This exercise intervention can improve fitness and clinical outcomes for this growing patient population.
Area of Science:
- Medical Science
- Exercise Physiology
- Pediatric Endocrinology
Background:
- Cystic fibrosis (CF) is a prevalent genetic disorder.
- Increased lifespan in CF patients has led to a rise in CF-related diabetes (CFRD).
- CFRD diagnosis negatively impacts survival, morbidity, and physical function.
Purpose of the Study:
- To explore the benefits of resistance training for individuals with CF and CFRD.
- To provide exercise recommendations for pediatric and adolescent populations with CF and CFRD.
Main Methods:
- Literature review on exercise interventions in CF and CFRD.
- Focus on resistance training modalities and their physiological effects.
- Analysis of existing data regarding exercise and clinical outcomes in CF/CFRD.
Main Results:
- Resistance training shows potential as a non-pharmacologic intervention.
- Exercise can improve fitness, body composition, and potentially clinical outcomes.
- Specific recommendations for safe and effective resistance training are needed.
Conclusions:
- Resistance training is a promising intervention for CF and CFRD.
- Further research and tailored exercise programs are warranted for this population.
- Exercise is a key component of comprehensive CF and CFRD management.
Abstract:
Cystic fibrosis (CF) is the most prevalent hereditary life-threatening disease in the Caucasian population. With the improvement in clinical care, individuals with CF are living longer, and CF-related diabetes (CFRD) has emerged as a major complication. The diagnosis of CFRD is associated with shortening survival, increasing morbidity, worsening physical capacity, and body composition. Engagement in exercise training has become a prominent nonpharmacologic intervention that aims to improve fitness and clinical outcomes in individuals with CF and CFRD. This column will specifically focus on the potential benefits of resistance training and provide recommendations for children and adolescents with CF and CFRD.
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