Inappropriate Subcutaneous Implantable Cardioverter Defibrillator Shocks Secondary to Cardiac Remodeling: A Unique...

Implantable cardioverter defibrillators (ICD) are used for the primary and secondary prevention of sudden cardiac death (SCD). Currently, two different modalities of ICDs are in use: transvenous (TV) and subcutaneous (S-ICD). The use of S-ICDs has been driven by several potential benefits of this technology: preservation of central venous vasculature, no risk of vascular or myocardial injury during implant, easier explanation, and lower risk of systemic infections. Inappropriate shocks are defined as shocks delivered for non-life-threatening arrhythmias or because of oversensing. Here, we present a case of a 58-year-old man who began experiencing inappropriate shocks three years after S-ICD placement. Careful analysis of the ICD showed T wave oversensing with no malfunction of the device. The shocks persisted even after reprogramming, leading to subsequent ICD removal and loop recorder implantation. The onset of shock episodes coincided with the improvement of left ventricular ejection fraction (LVEF). To the best of our knowledge, this is the first published report of cardiac remodeling leading to uncorrectable T wave oversensing that subsequently required S-ICD explant. This represents a potentially important limitation of S-ICD technology, especially as S-ICD use rises and medical therapy for cardiomyopathy continues to improve.