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Updated: Sep 3, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
Relation of Incident Type 1 Diabetes to Recent COVID-19 Infection: Cohort Study Using e-Health Record Linkage in
Paul M McKeigue1,2, Stuart McGurnaghan3, Luke Blackbourn3
11Usher Institute, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, Scotland, U.K.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was not linked to increased type 1 diabetes risk in a Scottish study. While type 1 diabetes incidence rose in children during the pandemic, the virus was not identified as the cause.
Area of Science:
- Endocrinology
- Virology
- Epidemiology
Background:
- Previous studies suggested a link between SARS-CoV-2 infection and increased type 1 diabetes incidence.
- This study aimed to validate these findings using precise diagnostic data in Scotland.
Discussion:
- The study found no association between SARS-CoV-2 infection over 30 days prior and type 1 diabetes.
- A short-term association was observed for infections within 30 days, but this may be confounded by testing frequency around diagnosis.
- Type 1 diabetes incidence in children aged 0-14 years increased by 20% during 2020-2021 compared to the 7-year average.
Key Insights:
- The cohort analysis did not support SARS-CoV-2 infection as a direct cause of increased type 1 diabetes incidence.
- The rise in type 1 diabetes among children during the pandemic period requires further investigation into other contributing factors.
Outlook:
- Further research is needed to understand the factors driving the increase in type 1 diabetes during the COVID-19 pandemic.
- Continued monitoring of diabetes incidence in relation to viral infections is crucial for public health.
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