Aquagenic keratoderma.

Area of Science:

• Dermatology
• Medical Case Reports

Background:

• Aquagenic keratoderma is a skin condition triggered by water exposure, presenting as papules and macerated plaques on palms and soles.
• It can be idiopathic or associated with conditions like cystic fibrosis, atopy, malnutrition, or certain medications.

Observation:

• A 17-year-old female with chronic abdominal pain presented with palmar "wrinkling" after water contact.
• Clinical examination revealed hyperlinearity, translucent papules, and macerated plaques. Dermoscopy showed whitish, anfractive structures resembling coral.
• Histopathology confirmed hyperkeratosis and acrosyringium dilation.

Findings:

• The patient was diagnosed with aquagenic keratoderma based on clinical and histological findings.
• Treatment initiated resulted in partial symptom improvement.

Implications:

• Aquagenic keratoderma is often underdiagnosed and can serve as a marker for systemic diseases, notably cystic fibrosis.
• The authors propose a descriptive nomenclature: "whitish macerated aquagenic plaques of the acrosyringium".
• Further case reporting is crucial for better understanding, management, and patient follow-up.