Blistering and aggressive paniculite cutaneous T-cell lymphoma.

Area of Science:

• Dermatology
• Hematology
• Pediatric Oncology

Background:

• Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare neoplastic proliferation of atypical T-cells in the subcutaneous fat.
• While typically indolent and affecting middle-aged adults, SPTCL can present aggressively and rarely occur in children.

Observation:

• A previously healthy 12-year-old male presented with a disseminated dermatosis.
• Clinical manifestations included vesicles, blisters, erythematous and hematonecrotic plaques, atrophic scars, and edema.

Findings:

• Histopathological examination confirmed limited cutaneous SPTCL with extensive epidermal necrosis.
• This case represents a rare pediatric presentation of SPTCL.

Implications:

• The diagnosis of SPTCL should be considered in children with similar clinical presentations, especially those refractory to initial treatments.
• Timely diagnosis and appropriate management are crucial for improving patient survival in pediatric SPTCL.
• This case underscores the need for increased awareness of SPTCL in pediatric dermatology and oncology.