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Gingival metastasis from primary hepatocellular carcinoma: a case report
Yuan Huang1, Yanqiu Bao2, Dongyuan Xu2
1Department of Gastroenterology, Yanbian University Hospital, Jilin, China.
The Journal of International Medical Research
|July 27, 2022
Summary
Hepatocellular carcinoma (HCC) rarely metastasizes to the oral cavity. This case report details a patient with liver cancer who developed a rare gingival metastasis, highlighting diagnostic considerations for oral masses.
Area of Science:
- Oncology
- Oral Pathology
- Surgical Pathology
Background:
- Hepatocellular carcinoma (HCC) is a prevalent global malignancy.
- Oral cavity metastasis from HCC is exceptionally rare, posing diagnostic challenges.
Observation:
- A 68-year-old male with diagnosed HCC developed a gingival metastasis 10 months post-hepatectomy.
- The metastasis was identified as a mandibular gingival mass.
Findings:
- The patient's condition progressed rapidly, leading to death 4 months after the metastasis diagnosis.
- Pathological examination and clinical history were crucial for diagnosing this rare metastatic presentation.
Implications:
- Mandibular gingival masses warrant consideration of metastatic disease in patients with a history of cancer.
- This case underscores the importance of thorough medical history and physical examination in diagnosing rare metastatic patterns of HCC.

