Related Experiment Video
Updated: Sep 3, 2025

Targeting the Corticospinal Tract in Neonatal Rats with a Double-Viral Vector using Combined Brain and Spine Surgery
Published on: June 30, 2021
Surgical Antimicrobial Prophylaxis in Neonates and Children Undergoing Neurosurgery: A RAND/UCLA Appropriateness
Susanna Esposito1, Mino Zucchelli2, Sonia Bianchini1
1Pediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
This consensus provides evidence-based antimicrobial prophylaxis recommendations for pediatric neurosurgery to prevent surgical site infections (SSIs). It aims to standardize antibiotic use in neonates and children undergoing various neurosurgical procedures.
Area of Science:
- Neurosurgery
- Infectious Disease
- Pediatrics
Background:
- Surgical site infections (SSIs) are serious complications in pediatric neurosurgery, impacting patient recovery and outcomes.
- Current peri-operative antibiotic prophylaxis practices often lack strong scientific evidence.
Purpose of the Study:
- To establish clear, evidence-based recommendations for antimicrobial prophylaxis in neonates and children undergoing neurosurgery.
- To standardize antibiotic use and prevent misuse in pediatric neurosurgical procedures.
Main Methods:
- A multidisciplinary consensus involving experts from leading Italian scientific societies.
- Review of the most updated scientific literature on antimicrobial prophylaxis in pediatric neurosurgery.
Main Results:
- The consensus document outlines specific recommendations for various neurosurgical scenarios, including craniotomy, spinal surgery, and shunt procedures.
- Provides guidance on antimicrobial prophylaxis for neonates and children undergoing neurosurgery.
Conclusions:
- This consensus offers a comprehensive and up-to-date guide for clinicians managing pediatric neurosurgery patients.
- Aims to standardize peri-operative antibiotic management, reduce SSIs, and optimize patient functional recovery.
Related Concept Videos
Suctioning the Nasopharyngeal Airway
Equipment Required
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Hand hygiene
Hand washing...
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...

