Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open and closed-loop control systems01:17

Open and closed-loop control systems

960
Control systems are foundational elements in automation and engineering. They are broadly categorized into open-loop and closed-loop systems. These classifications hinge on the presence or absence of feedback mechanisms, significantly influencing the system's performance, complexity, and application.
An open-loop control system operates without feedback from the output. It consists of two primary elements: the controller and the controlled process. The controller receives an input signal...
960
Feedback control systems01:26

Feedback control systems

407
Feedback control systems are categorized in various ways based on their design, analysis, and signal types.
Linear feedback systems are theoretical models that simplify analysis and design. These systems operate under the principle that their output is directly proportional to their input within certain ranges. For instance, an amplifier in a control system behaves linearly as long as the input signal remains within a specific range. However, most physical systems exhibit inherent nonlinearity...
407
Control Volume and System Representations01:16

Control Volume and System Representations

1.2K
Two key frameworks are employed to analyze mass, energy, and momentum transfer: the control volume approach and the system approach. These frameworks offer different perspectives, depending on whether the focus is on a specific region in space (control volume approach) or a defined mass of fluid (system approach).
The control volume approach considers a stationary region in space through which fluid flows. This region is bounded by a control surface.  For instance, in the case of water...
1.2K
One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance00:56

One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance

135
Clearance is a key pharmacokinetic parameter that quantifies the volume of body fluid from which a drug is entirely removed within a specific time frame. It is crucial in assessing how a drug is eliminated from the body and has critical clinical applications.
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...
135
Multiple Pipe Systems01:21

Multiple Pipe Systems

832
Multipipe systems consist of complex configurations of interconnected pipes designed to transport fluids efficiently across intricate networks. They are essential in engineering applications requiring precise control over flow distribution, pressure, and head loss. They are categorized into series, parallel, loop, and network configurations, each distinguished by unique flow characteristics and applications.
Series Configuration
In a series configuration, fluid flows sequentially from one pipe...
832
Controlled-Current Coulometry: Overview01:27

Controlled-Current Coulometry: Overview

292
Controlled current coulometry, also known as amperostatic coulometry, is a technique used in electrochemical analysis to measure the quantity of a substance through the controlled passage of current. It involves the application of a constant current to an electrochemical cell containing the analyte of interest. As the current flows through the cell, the analyte undergoes a redox reaction at the electrode surface, resulting in a charge transfer. By monitoring the time required for a certain...
292

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The rise of medical autonomous care, a paradigmatic turning point for military and civilian delivery of health care.

Journal of critical care·2026
Same author

Deep Learning-Based Tracking of Neurovascular Features Toward Semi-Automated Ultrasound-Guided Peripheral Nerve Blocks by Non-Specialists.

Bioengineering (Basel, Switzerland)·2026
Same author

Comparison of Controller Logics for Automating Vasopressor Administration Using a Hardware-in-Loop Test Platform.

Bioengineering (Basel, Switzerland)·2026
Same author

Validation of a Wearable Photoplethysmography-Based Sensor for Compensatory Reserve Measurement Monitoring in Simulated Human Hemorrhage.

Sensors (Basel, Switzerland)·2026
Same author

Experimental evaluation of a real-time implementation of compensatory reserve measurement in a human model of hemorrhagic shock.

Frontiers in bioengineering and biotechnology·2026
Same author

Development of a vasopressor control module for testing hemorrhagic shock resuscitation controllers.

Biomedical engineering online·2026

Related Experiment Video

Updated: Sep 3, 2025

Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications
09:08

Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications

Published on: August 30, 2018

12.5K

Closed-Loop Controlled Fluid Administration Systems: A Comprehensive Scoping Review.

Guy Avital1,2,3, Eric J Snider1, David Berard1

  • 1U.S. Army Institute of Surgical Research, JBSA Fort Sam Houston, San Antonio, TX 78234, USA.

Journal of Personalized Medicine
|July 27, 2022
PubMed
Summary

Physiological closed-loop controlled systems enhance patient care accuracy and reduce clinician workload. This review maps current technologies and future advancements in closed-loop systems for precise medical management.

Keywords:
artificial intelligenceautomatedautonomousclosed loopcontrollerdecision supportfluid managementfluid resuscitationfluid therapyscoping review

More Related Videos

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

30.6K
High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
10:22

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

13.9K

Related Experiment Videos

Last Updated: Sep 3, 2025

Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications
09:08

Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications

Published on: August 30, 2018

12.5K
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

30.6K
High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
10:22

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

13.9K

Area of Science:

  • Biomedical Engineering
  • Clinical Informatics
  • Physiological Monitoring

Background:

  • Physiological closed-loop controlled systems are increasingly adopted in clinical practice.
  • These systems offer more accurate, goal-directed patient care and reduce cognitive load for clinicians.
  • They standardize patient management, reducing variability in care delivery.

Purpose of the Study:

  • To conduct a comprehensive scoping review of physiological closed-loop controlled systems.
  • To assess the current technological landscape and describe available or developing systems.
  • To suggest future advancements in the field of closed-loop control.

Main Methods:

  • Comprehensive scoping review methodology.
  • Identification and discussion of distinct closed-loop systems.
  • Analysis of controller designs, from simple to complex, including adaptive properties.

Main Results:

  • Ten distinct physiological closed-loop controlled systems were identified and discussed.
  • Systems range from theoretical models to FDA-approved products.
  • Controller designs vary, incorporating physiological models and adaptive capabilities.

Conclusions:

  • Closed-loop systems offer clear advantages in fluid management and administration, particularly in critical care settings.
  • These technologies are maturing, with a spectrum of development from in silico testing to commercial availability.
  • Further advancements are anticipated in the coming years for closed-loop system applications.