Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

17β-Estradiol mitigates ovariectomy-induced defects in mitochondrial bioenergetics and redox balance after VML injury in female mice.

American journal of physiology. Cell physiology·2026
Same author

The Effect of Occupational Integration on Musculoskeletal Injury in Female Marines in the Fleet: An Epidemiological Cohort Study.

Military medicine·2026
Same author

Loss of ovarian hormones modulates sex-specific metabolic adaptations to volumetric muscle loss.

American journal of physiology. Cell physiology·2026
Same author

Beyond the first bout: Adaptations to repeated injuries across physiological and pathological conditions.

Physiological reports·2026
Same author

Finishing Barrow Skeletal Muscle Performance and Fatigue Response to Large-Dose Nicotinamide Riboside Supplementation.

Metabolites·2026
Same author

Neurometabolic substrate utilization governs oxidative phosphorylation conductance in cortex and hippocampus.

Journal of neurophysiology·2026

Related Experiment Video

Updated: Sep 3, 2025

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes
11:32

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

Published on: December 8, 2014

12.9K

Lower-Extremity Neuromuscular Function Following Concussion: A Preliminary Examination.

Landon B Lempke1,2,3,4, Jarrod A Call2,5, Matthew C Hoch6

  • 1UGA Concussion Research Laboratory, University of Georgia, Athens, GA,USA.

Journal of Sport Rehabilitation
|July 27, 2022
PubMed
Summary

Concussed individuals show no differences in voluntary or involuntary muscle activation when symptom-free. However, they report higher pain during testing, suggesting altered pain perception post-concussion.

Keywords:
interpolated twitchkinesiophobiamild traumatic brain injurysensorimotor

More Related Videos

An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System
07:02

An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System

Published on: January 12, 2011

15.9K
A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion
10:31

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion

Published on: September 25, 2014

13.5K

Related Experiment Videos

Last Updated: Sep 3, 2025

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes
11:32

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

Published on: December 8, 2014

12.9K
An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System
07:02

An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System

Published on: January 12, 2011

15.9K
A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion
10:31

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion

Published on: September 25, 2014

13.5K

Area of Science:

  • Neurology
  • Sports Medicine
  • Rehabilitation Science

Background:

  • Concussion can alter neuromuscular function, potentially increasing musculoskeletal injury risk.
  • Previous research focused only on voluntary muscle activation, limiting understanding of underlying mechanisms.
  • This study investigates both voluntary and involuntary muscle activation in concussed individuals.

Purpose of the Study:

  • To compare voluntary and involuntary quadriceps muscle activation in college-aged individuals who have experienced a concussion versus healthy controls.
  • To determine if neuromuscular function deficits persist even when concussed individuals are symptom-free.
  • To explore potential links between altered muscle activation and post-concussion injury risk.

Main Methods:

  • A prospective, cross-sectional cohort laboratory study design was employed.
  • Participants included 24 college-aged individuals (concussed and healthy controls).
  • The superimposed burst (SB) assessment measured quadriceps maximal voluntary isometric contraction torque, electrically stimulated SB torque, and central activation ratio.

Main Results:

  • No statistically significant differences were found in maximal voluntary isometric contraction torque, SB torque, or central activation ratio between concussed and control groups.
  • Bodyweight normalization did not alter these findings.
  • Participants with a concussion reported significantly higher pain during the SB assessment compared to controls.

Conclusions:

  • Symptom-free concussed individuals do not exhibit altered voluntary or involuntary quadriceps neuromuscular function compared to healthy controls.
  • The increased risk of musculoskeletal injury after concussion may not be directly linked to deficits in lower-extremity muscle activation.
  • Concussed participants' heightened pain perception during neuromuscular testing suggests potential somatosensory or perceptual changes warranting further investigation.