Related Experiment Video
Updated: Sep 3, 2025

Quantification of Drosophila melanogaster Grooming Behavior for Evaluation of Excessive Grooming Phenotypes
Published on: March 21, 2025
[A female with excessive wrinkling of the hands]
Jonathan W J Melger1,2, Patricia J C Knijnenburg1, Inge B Mathijssen1
1Amsterdam UMC, locatie AMC, afd. Humane Genetica, Amsterdam.
Abstract:
A 23-year-old female complained of excessive wrinkling of her hands after brief exposure to water. The symptoms were characteristic for the diagnosis aquagenic wrinkling of the palms (AWP). This disorder is frequently associated with cystic fibrosis (CF) or CF carrier state. DNA analysis of the cystic fibrosis gene is indicated.
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